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Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL)

Abteilung Mikrobiologie
Technische Universität München
Weihenstephaner Berg 3
D-85350 Freising





Dr. Genia Lücking
Biologist

Phone +49 (81 61) 71 5570
Fax + 49 (81 61) 71 44 92
E-mail: genia.luecking @ wzw.tum.de


                                

Research career

since 2009  Postdoc scientist at the Unit of Microbiology, ZIEL, TU München

2005 - 2009 PhD at the Unit of Microbiology, ZIEL, TU München: "Molecular 
                  characterization of cereulide synthesis in emetic Bacillus cereus"

2004           Diploma thesis at the Department of Microbiology, Julius-Maximilians-University
                  Würzburg: "Characterization of putative virulence factors in Bordetella holmesii"

1999-2004    studies in biology at the Julius-Maximillian-University Würzburg
                                                                                                                                     


Publications

Lücking G, Frenzel E, Rütschle A, Marxen S, Stark TD, Hofmann T, Scherer S, Ehling-Schulz M (2015) Ces locus embedded proteins control the non-ribosomal synthesis of the cereulide toxin in emetic Bacillus cereus on multiple levels. Front Microbiol 6:1101.

Marxen S, Stark TD, Rütschle A, Lücking G, Frenzel E, Scherer S, Ehling-Schulz M, Hofmann T (2015) Multiparametric quantitation of the Bacillus cereus toxins cereulide and isocereulides A-G in Foods. J. Agric Food chem 63(37):8307.

Marxen S, Stark TD, Rütschle A, Lücking G, Frenzel E, Scherer S, Ehling-Schulz M, Hofmann T (2015) Depsipeptide intermediates interrogate proposed biosynthesis of cereulide, the emetic toxin of Bacillus cereus. Sci Rep. 5:10637.

Marxen S, Stark TD, Frenzel E, Rütschle A, Lücking G, Pürstinger G, Pohl EE, Scherer S, Ehling-Schulz M, Hofmann T (2015) Chemodiversity of cereulide, the emetic toxin of Bacillus cereus. Anal Bioanal Chem 407(9):2439-53.

Lücking G, Stoeckel M, Atamer Z, Hinrichs J, Ehling-Schulz M (2013) Characterization of aerobic spore-forming bacteria associated with industrial dairy processing environments and product spoilage. Int J Food Microbiol166:270-279.

Stark, T., Marxen, S., Rütschle, A., Lücking, G., Scherer, S., Ehling-Schulz, M., Hofmann, T. (2013) Mass spectrometric profiling of Bacillus cereus strains and quantitation of the emetic toxin cereulide by means of stable isotope dilution analysis and HEp-2 bioassay. Analytical and bioanalytical chemistry 405:191-201. 


Frenzel, E., Doll, V., Pauthner, M., Lücking, G., Scherer, S., Ehling-Schulz, M. (2012) CodY orchestrates the expression of virulence determinants in emetic Bacillus cereus by impacting key regulatory circuits. Molecular microbiology 85:67-88. 

Witthuhn, M., Lücking, G., Atamer, Z., Ehling-Schulz, M., Hinrichs J. (2011) Thermal resistance of aerobic spore formers isolated from food products. International Journal of Dairy Technology 64:486-493. 

Dommel, M.K., Lücking, G., Scherer, S., Ehling-Schulz, M. (2011) Transcriptional kinetic analyses of  cereulide synthetase genes with respect to growth, sporulation and emetic toxin production in Bacillus cereus. Food microbiology 28:284-290. 

Lücking, G., Dommel, M.K., Scherer, S., Fouet, A., Ehling-Schulz, M. (2009) Cereulide synthesis in emetic Bacillus cereus in controlled by the transition state regulator AbrB, but not by the virulence regulator PlcR. Microbiology 155:922-931. 

Serra, D.O., Lücking, G., Weiland, F., Schulz, S., Gorg, A., Yantorno, O.M., Ehling-Schulz, M. (2008) Proteome approaches combined with Fourier transform infrared spectroscopy revealed a distinctive biofilm physiology in Bordetella pertussis. Proteomics 8:4995-5010. 

Elmasri, H., Liedtke, D., Lücking, G., Volff, J.N., Gessler, M., Winkler, C. (2004) her7 and hey1, but not lunatic fringe show dynamic expression during somitogenesis in medaka (Oryzias latipes). Gene expression patterns. GEP 4:553-559. 




























Aktuelles

Forschungspreis
Otto-von-Guericke Forschungspreis für Siegfried Scherer

Preisverleihung
Innovationspreis für Siegfried Scherer

Paper
Spoilage of Microfiltered and Pasteurized Extended Shelf Life Milk Is Mainly Induced by Psychrotolerant Spore-Forming Bacteria that often Originate from Recontamination

Paper
Transcriptional and translational regulation by RNA thermometers, riboswitches and the sRNA DsrA in Escherichia coli O157:H7 Sakai under combined cold and osmotic stress adaptation. (2016)

Paper
Hysteresis in myo-inositol utilization by Salmonella Typhimurium (2016)

Paper
Probiotic Enterococcus faecalis Symbioflor® down regulates virulence genes of EHEC in vitro and decrease pathogenicity in a Caenorhabditis elegans model (2017)

Paper
Draft Genome Sequence of Lysinibacillus xylanilyticus SR-86 (Nov. 2016)

Paper
Permanent colonization of creek sediments, creek water and limnic water plants by four Listeria species in low population densities (November 2016)

Paper
Draft Genome Sequence of the Xanthan Producer Xanthomonas campestris LMG 8031 (Oktober 2016)

Paper
Comparative Bioinformatics and Experimental Analysis of the Intergenic Regulatory Regions of Bacillus cereus hbl and nhe Enterotoxin Operons and the Impact of CodY on Virulence Heterogeneity (Mai 2016)

Paper
Regulation of fucose and 1,2-propanediol utilization by Salmonella enterica serovar Typhimurium (März 2016)

Paper
Acidified nitrite inhibits proliferation of Listeria monocytogenes - Transcriptional analysis of a preservation method (März 2016)

Berufung Expertenrat
Prof. Dr. Siegfried Scherer wurde in den Expertenrat für Lebensmittelsicherheit des Bayerischen Staatsministeriums für Umwelt und Verbraucherschutz berufen.

Paper
Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC)

Paper
A sensitive and robust method for direct determination of lipolytic activity in natural milk environment (März 2016, online first)

Paper
Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting (Dez. 2015).

Paper
Massive horizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe (Nov. 2015)

Paper
Chemodiversity of cereulide, the emetic Toxin of Bacillus cereus (2015)